Supplement Reviews This examination revealed that participants who had not responded to the weight management program had had diabetes for a longer time — namely, about 3.8 years vs. 2.7 years.
But in other respects, both nonresponders and responders proved to be similar: they had lost about the same amount of weight, exhibited a similar reduction of liver and pancreatic fat, and had a similar downregulation of blood triglycerides.
The one difference between responders and nonresponders was this: that the people who regained normal blood glucose levels after the intervention exhibited early, constant improvement in the function of pancreatic beta cells.
When beta cells secrete insulin, they do so in two phases, the first of which amounts to a brief spike in insulin levels and takes about 10 minutes. People with type 2 diabetes typically do not experience it.
But in other respects, both nonresponders and responders proved to be similar: they had lost about the same amount of weight, exhibited a similar reduction of liver and pancreatic fat, and had a similar downregulation of blood triglycerides.
The one difference between responders and nonresponders was this: that the people who regained normal blood glucose levels after the intervention exhibited early, constant improvement in the function of pancreatic beta cells.
When beta cells secrete insulin, they do so in two phases, the first of which amounts to a brief spike in insulin levels and takes about 10 minutes. People with type 2 diabetes typically do not experience it.
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